Physics – Condensed Matter – Mesoscale and Nanoscale Physics
Scientific paper
2010-04-27
Appl. Phys. Lett. vol 96, 163701 (2010).
Physics
Condensed Matter
Mesoscale and Nanoscale Physics
3 pages, accepted to Appl. Phys. Lett.
Scientific paper
We provide an experimental demonstration that the focusing of ionic currents in a micron size hole connecting two chambers can produce local temperature increases of up to $100^\circ$ C with gradients as large as $1^\circ$ K$\mu m^{-1}$. We find a good agreement between the measured temperature profiles and a finite elements-based numerical calculation. We show how the thermal gradients can be used to measure the full melting profile of DNA duplexes within a region of 40 $\mu$m. The possibility to produce even larger gradients using sub-micron pores is discussed.
Bockelmann U.
Isambert Hervé
Laufer L.
Meller Amit
Tsori Yoav
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