An Analytical Approach to the Protein Designability Problem

Details An Analytical Approach to the Protein Designability Problem An Analytical Approach to the Protein Designability Problem

1999-04-27

arxiv.org/abs/cond-mat/9904377v1

Physics

Condensed Matter

Soft Condensed Matter

16 pages 4 figures

Scientific paper

10.1103/PhysRevLett.83.4437

We present an analytical method for determining the designability of protein structures. We apply our method to the case of two-dimensional lattice structures, and give a systematic solution for the spectrum of any structure. Using this spectrum, the designability of a structure can be estimated. We outline a heirarchy of structures, from most to least designable, and show that this heirarchy depends on the potential that is used.

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