Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
2001-12-11
Physics
Condensed Matter
Soft Condensed Matter
12 pages, 17 figures
Scientific paper
Mechanical stretching of secondary structures is studied through molecular dynamics simulations of a Go-like model. Force vs. displacement curves are studied as a function of the stiffness and velocity of the pulling device. The succession of stretching events, as measured by the order in which contacts are ruptured, is compared to the sequencing of events during thermal folding and unfolding. Opposite cross-correlations are found for an $\alpha$-helix and a $\beta$-hairpin structure. In a tandem of two $\alpha$-helices, the two constituent helices unravel nearly simultaneously. A simple condition for simultaneous vs. sequential unraveling of repeat units is presented.
Cieplak Marek
Hoang Trinh Xuan
Robbins Mark. O.
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