The pulling force of a single DNA molecule condensed by spermidine

Details The pulling force of a single DNA molecule condensed by spermidine The pulling force of a single DNA molecule condensed by spermidine

2003-10-14

arxiv.org/abs/cond-mat/0310321v3

Physica A 349 (2005) 563

Physics

Condensed Matter

Soft Condensed Matter

4 pages, 4 figures. Small change in the text, no change in results

Scientific paper

10.1016/j.physa.2004.11.013

In a recent experiment, a single DNA double helix is stretched and relaxed in the presence of spermidine, a short positive polyelectrolyte, and the pulling force is measured as a function of DNA extension. In a certain range of spermidine concentration, a force plateau appears whose value shows maximum as a function of spermidine concentration. We present a quantitative theory of this plateau force based on the theory of reentrant condensation and derive almost parabolic behavior of the plateau force as a function of the logarithm of the spermidine concentration in the range of condensation. Our result is in good agreement with experimental data.

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