Strand separation in negatively supercoiled dna

Details Strand separation in negatively supercoiled dna Strand separation in negatively supercoiled dna

2003-06-18

arxiv.org/abs/cond-mat/0306476v1

Physics

Condensed Matter

Statistical Mechanics

20 pages

Scientific paper

We consider a model for strand separation in negatively supercoiled dna, and study the effect of supercoiling on the localization of denaturation, using notions from statistical mechanics. The model is based on on mean field Ising system, coupled with a random field one dimensional ISing model. The effect of the word in AT and Gc associated with the DNA on localization of denaturation is studied under the hypothesis of small perimeter.

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