Physics – Condensed Matter – Statistical Mechanics
Scientific paper
2009-02-11
Proceedings of the III. Int. Conf. on Large Scale Simulations of Complex Systems, Condensed Matter, and Fusion Plasma, AIP Con
Physics
Condensed Matter
Statistical Mechanics
28 pages, 10 figures, 2 tables
Scientific paper
Protein folding, peptide aggregation and crystallization, as well as adsorption of molecules on soft or solid substrates have an essential feature in common: In all these processes, structure formation is guided by a collective, cooperative behavior of the molecular subunits lining up to build chainlike macromolecules. Proteins experience conformational transitions related to thermodynamic phase transitions. For chains of finite length, an important difference of crossovers between conformational (pseudo)phases is, however, that these transitions are typically rather smooth processes, i.e., thermodynamic activity is not necessarily signalized by strong entropic or energetic fluctuations. Nonetheless, in order to understand generic properties of molecular structure-formation processes, the analysis of mesoscopic models from a statistical physics point of view enables first insights into the nature of conformational transitions in small systems. Here, we review recent results obtained by means of sophisticated generalized-ensemble computer simulations of minimalistic coarse-grained models.
Bachmann Michael
Janke Wolfhard
No associations
LandOfFree
Mesoscopic Properties of Molecular Folding and Aggregation Processes does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Mesoscopic Properties of Molecular Folding and Aggregation Processes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Mesoscopic Properties of Molecular Folding and Aggregation Processes will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-488288