Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for in vivo Cancer Therapy

Details Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for in vivo Cancer Therapy Supramolecular Stacking of Doxorubicin on Carbon Nanotubes for in vivo Cancer Therapy

2009-10-03

arxiv.org/abs/0910.0567v1

Physics

Condensed Matter

Materials Science

Angew. Chem. Int. Ed. 48, 7668-7672 (2009)

Scientific paper

Many therapeutic advantages such as prolonged circulation in the blood, increased tumor drug uptake, enhanced therapeutic efficacy, and markedly reduced toxic side effects are provided by a carbon nanotube based chemotherapeutic formulation. In this system, doxorubicin (DOX) is loaded onto the sidewalls of functionalized single-walled carbon nanotubes by supramolecular pi-pi stacking.

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