Fitness landscapes and evolution

Physics – Condensed Matter

Scientific paper

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27 pages, no figures, plain LaTeX (article.sty)

Scientific paper

The concept of fitness is introduced, and a simple derivation of the Fundamental Theorem of Natural Selection (which states that the average fitness of a population increases if its variance is nonzero) is given. After a short discussion of the adaptative walk model, a short review is given of the quasispecies approach to molecular evolution and to the error threshold. The relevance of flat fitness landscapes to molecular evolution is stressed. Finally a few examples which involve wider concepts of fitness, and in particular two-level selection, are shortly reviewed.

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