Master equation approach to protein folding

Details Master equation approach to protein folding Master equation approach to protein folding

1998-06-25

arxiv.org/abs/cond-mat/9806313v3

J. Cond. Matt. 2, 369 (1999)

Physics

Condensed Matter

Statistical Mechanics

Latex, 6 pages, including 7 postscript figures. Typos corrected

Scientific paper

The dynamics of two 12-monomer heteropolymers on the square lattice is studied exactly within the master equation approach. The time evolution of the occupancy of the native state is determined. At low temperatures, the median folding time follows the Arrhenius law and is governed by the longest relaxation time. For good folders, significant kinetic traps appear in the folding funnel whereas for bad folders, the traps also occur in non-native energy valleys.

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