Direct Determination of DNA Twist-Stretch Coupling

Physics – Condensed Matter – Soft Condensed Matter

Scientific paper

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Plain TeX file; uses harvmac and epsf; .ps also available at http://dept.physics.upenn.edu/~nelson/twiststretch.ps or http:/

Scientific paper

10.1209/epl/i1997-00231-y

The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally-constrained single molecules give the first direct measurement of this important material parameter. We extract its value from a recent experiment of Strick et al. [Science 271 (1996) 1835] and find rough agreement with an independent experimental estimate recently given by Marko. We also present a very simple microscopic theory predicting a value comparable to the one observed.

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