Statistical mechanics of warm and cold unfolding in proteins

Physics – Condensed Matter

Scientific paper

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5 pages, REVTex, 4 Postscript figures

Scientific paper

10.1007/s100510050537

We present a statistical mechanics treatment of the stability of globular
proteins which takes explicitly into account the coupling between the protein
and water degrees of freedom. This allows us to describe both the cold and the
warm unfolding, thus qualitatively reproducing the known thermodynamics of
proteins.

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