Work probability distribution in single molecule experiments

Details Work probability distribution in single molecule experiments Work probability distribution in single molecule experiments

2004-11-25

arxiv.org/abs/cond-mat/0411654v2

Europhys. Lett., 69 (4), 643-649 (2005).

Physics

Condensed Matter

Soft Condensed Matter

To appear on EPL

Scientific paper

10.1209/epl/i2004-10390-3

We derive and solve a differential equation satisfied by the probability distribution of the work done on a single biomolecule in a mechanical unzipping experiment. The unzipping is described as a thermally activated escape process in an energy landscape. The Jarzynski equality is recovered as an identity, independent of the pulling protocol. This approach allows one to evaluate easily, by numerical integration, the work distribution, once a few parameters of the energy landscape are known.

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