Unzipping DNA : A hypothesis on correlation during replication

Details Unzipping DNA : A hypothesis on correlation during replication Unzipping DNA : A hypothesis on correlation during replication

2000-10-09

arxiv.org/abs/cond-mat/0010132v2

Indian J. Phys. A 85A, 69 (2002)

Physics

Condensed Matter

Statistical Mechanics

5 pages, latex/revtex, 1 eps figures. Corrected typos, reference list updated. Proceedings of CMDAYS2K, held at Guru Ghasidas

Scientific paper

Based on the result of an unzipping phase transition by a force in a model of DNA, we hypothesize that the DnaA-type proteins act as a pulling agent with a force slightly less than the critical force for unzipping. The dynamic (space-time) correlation of unzipping then drives the subsequent events of replication. In such a correlation driven scenario, there is no need of a replisome as a structural unit and this elusive replisome may not exist at all.

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