Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
1997-03-28
Physics
Condensed Matter
Soft Condensed Matter
RevTex, 24 pages, 15 eps figs, uses cite.sty, Biophysical J
Scientific paper
10.1016/S0006-3495(98)74029-9
We present a general theoretical analysis of semiflexible filaments subject to viscous drag or point forcing. These are the relevant forces in dynamic experiments designed to measure biopolymer bending moduli. By analogy with the ``Stokes problems" in hydrodynamics (fluid motion induced by that of a wall bounding a viscous fluid), we consider the motion of a polymer one end of which is moved in an impulsive or oscillatory way. Analytical solutions for the time-dependent shapes of such moving polymers are obtained within an analysis applicable to small-amplitude deformations. In the case of oscillatory driving, particular attention is paid to a characteristic length determined by the frequency of oscillation, the polymer persistence length, and the viscous drag coefficient. Experiments on actin filaments manipulated with optical traps confirm the scaling law predicted by the analysis and provide a new technique for measuring the elastic bending modulus. A re-analysis of several published experiments on microtubules is also presented.
Goldstein Raymond E.
Ott Albrecht
Riveline Daniel X.
Wiggins Chris H.
No associations
LandOfFree
Trapping and Wiggling: Elastohydrodynamics of Driven Microfilaments does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.
If you have personal experience with Trapping and Wiggling: Elastohydrodynamics of Driven Microfilaments, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trapping and Wiggling: Elastohydrodynamics of Driven Microfilaments will most certainly appreciate the feedback.
Profile ID: LFWR-SCP-O-28203