Terahertz Biomems for Enzymatic Catalysis Monitoring

Details Terahertz Biomems for Enzymatic Catalysis Monitoring Terahertz Biomems for Enzymatic Catalysis Monitoring

2009-07-07

arxiv.org/abs/0907.1162v1

5th International Conference on Microtechnologies in Medicine and Biology, Qu\'ebec City : Canada (2009)

Physics

Condensed Matter

Materials Science

Scientific paper

This work focuses on the fabrication and use of a Biological Micro-ElectroMechanical System (BioMEMS) for TeraHertz (THz) detection and characterization of enzymatic catalysis reactions. The fluidic microdevice was fabricated using traditional lithographic techniques. It was then functionalized by reactive amine functions using plasma polymerized allylamine (pp-allylamine), followed by enzyme immobilization inside the microchannels. The enzymatic reaction was controlled by fluorescent microscopy before being analysed by sub-THz spectroscopy in the frequency range 0.06--0.11 THz. The preliminary results show the feasibility of terahertz monitoring of the biocatalysis reaction.

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