Substrate Specificity of Peptide Adsorption: A Model Study

Details Substrate Specificity of Peptide Adsorption: A Model Study Substrate Specificity of Peptide Adsorption: A Model Study

2007-10-22

arxiv.org/abs/0710.4107v1

Phys. Rev. E 73, 020901(1-4)(R) (2006)

Physics

Condensed Matter

Soft Condensed Matter

5 pages, 2 figures

Scientific paper

10.1103/PhysRevE.73.020901

Applying the contact density chain-growth algorithm to lattice heteropolymers, we identify the conformational transitions of a nongrafted hydrophobic-polar heteropolymer with 103 residues in the vicinity of a polar, a hydrophobic, and a uniformly attractive substrate. Introducing only two system parameters, the numbers of surface contacts and intrinsic hydrophobic contacts, respectively, we obtain surprisingly complex temperature and solvent dependent, substrate-specific pseudo-phase diagrams.

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