Statistical mechanics of RNA folding: a lattice approach

Details Statistical mechanics of RNA folding: a lattice approach Statistical mechanics of RNA folding: a lattice approach

2003-03-20

arxiv.org/abs/cond-mat/0303421v1

Physics

Condensed Matter

Soft Condensed Matter

8 pages, 9 figures

Scientific paper

10.1103/PhysRevE.68.051904

We propose a lattice model for RNA based on a self-interacting two-tolerant trail. Self-avoidance and elements of tertiary structure are taken into account. We investigate a simple version of the model in which the native state of RNA consists of just one hairpin. Using exact arguments and Monte Carlo simulations we determine the phase diagram for this case. We show that the denaturation transition is first order and can either occur directly or through an intermediate molten phase.

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