Stable integration of isolated cell membrane patches in a nanomachined aperture: a step towards a novel device for membrane physiology

Details Stable integration of isolated cell membrane patches in a nanomachined aperture: a step towards a novel device for membrane physiology Stable integration of isolated cell membrane patches in a nanomachined aperture: a step towards a novel device for membrane physiology

1999-10-14

arxiv.org/abs/cond-mat/9910217v1

Physics

Condensed Matter

Soft Condensed Matter

Scientific paper

We investigate the microscopic contact of a cell/semiconductor hybrid. The
semiconductor is nanostructured with the aim of single channel recording of ion
channels in cell membranes. This approach will overcome many limitations of the
classical patch-clamp technique. The integration of silicon-based devices
'on-chip' promises novel types of experiments on single ion channels.

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