Recovery of Protein Structure from Contact Maps

Details Recovery of Protein Structure from Contact Maps Recovery of Protein Structure from Contact Maps

1997-05-21

arxiv.org/abs/cond-mat/9705211v1

Physics

Condensed Matter

Soft Condensed Matter

27 pages, RevTex, 12 figures included

Scientific paper

We present an efficient algorithm to recover the three dimensional structure of a protein from its contact map representation. First we show that when a physically realizable map is used as target, our method generates a structure whose contact map is essentially similar to the target. Furthermore, the reconstructed and original structures are similar up to the resolution of the contact map representation. Next we use non-physical target maps, obtained by corrupting a physical one; in this case our method essentially recovers the underlying physical map and structure. Hence our algorithm will help to fold proteins, using dynamics in the space of contact maps. Finally we investigate the manner in which the quality of the recovered structure degrades when the number of contacts is reduced.

Affiliated with

Also associated with

No associations

Rating

Recovery of Protein Structure from Contact Maps does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Recovery of Protein Structure from Contact Maps, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recovery of Protein Structure from Contact Maps will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-219573