Quasispecies evolution in general mean-field landscapes

Details Quasispecies evolution in general mean-field landscapes Quasispecies evolution in general mean-field landscapes

2001-05-21

arxiv.org/abs/cond-mat/0105379v2

Europhys. Lett. 57, 745-751 (2002)

Physics

Condensed Matter

Disordered Systems and Neural Networks

6 pages, 2 figures, Europhysics Letters style (included) Finite-size scaling analysis sketched. To appear in Europhysics Lette

Scientific paper

10.1209/epl/i2002-00526-5

I consider a class of fitness landscapes, in which the fitness is a function of a finite number of phenotypic "traits", which are themselves linear functions of the genotype. I show that the stationary trait distribution in such a landscape can be explicitly evaluated in a suitably defined "thermodynamic limit", which is a combination of infinite-genome and strong selection limits. These considerations can be applied in particular to identify relevant features of the evolution of promoter binding sites, in spite of the shortness of the corresponding sequences.

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