Protein crystals and charged surfaces: interactions and heterogeneous nucleation

Details Protein crystals and charged surfaces: interactions and heterogeneous nucleation Protein crystals and charged surfaces: interactions and heterogeneous nucleation

2003-04-16

arxiv.org/abs/cond-mat/0304369v1

Physical Review E 67, 061907 (2003)

Physics

Condensed Matter

Soft Condensed Matter

7 pages, 4 figures

Scientific paper

10.1103/PhysRevE.67.061907

As proteins typically have charges of around 10, they will interact strongly with charged surfaces. We calculate the electrostatic contribution to the interaction of crystals of protein with charged surfaces. The surfaces repel like-charged crystals and attract oppositely-charged crystals, with free energies which can be easily several kT per protein molecule brought into contact with the surface. This means that oppositely charged surfaces can act as a nucleant, they can induce nucleation of a protein crystal by lowering the free energy barrier to heterogeneous nucleation of the crystal from a dilute solution.

Affiliated with

Also associated with

No associations

Rating

Protein crystals and charged surfaces: interactions and heterogeneous nucleation does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Protein crystals and charged surfaces: interactions and heterogeneous nucleation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein crystals and charged surfaces: interactions and heterogeneous nucleation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-608246