Protein crystallization in confined geometries

Details Protein crystallization in confined geometries Protein crystallization in confined geometries

2003-09-16

arxiv.org/abs/cond-mat/0309373v1

Physics

Condensed Matter

Soft Condensed Matter

4 pages, 5 figures

Scientific paper

We studied the crystallization of a globular protein, lysozyme, in the cubic phase of the lipid monoolein. The solubility of lysozyme in salt solution decreased by a factor of $\sim 4$ when confined in cubic phase. Calculations and Monte Carlo simulations show that this can be explained by the {\it confinement} of lysozyme molecules to the narrow water cells in the cubic phase.

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