Protein Adsorption on Lipid Monolayers at their Coexistence Region

Details Protein Adsorption on Lipid Monolayers at their Coexistence Region Protein Adsorption on Lipid Monolayers at their Coexistence Region

1998-03-21

arxiv.org/abs/cond-mat/9803262v1

J. Phys. II (France) 6, 1023 (1996)

Physics

Condensed Matter

Soft Condensed Matter

19 pages, 7 figures, Latex2.09 only

Scientific paper

We investigate theoretically the behavior of proteins as well as other large macromolecules which are incorporated into amphiphilic monolayers at the air-water interface. We assume the monolayer to be in the coexistence region of the ``main'' transition, where domains of the liquid condensed phase coexist with the liquid expanded background. Using a simple mean-field free energy accounting for the interactions between proteins and amphiphilic molecules, we obtain the spatial protein distribution with the following characteristics. When the proteins preferentially interact with either the liquid condensed or liquid expanded domains, they will be dissolved in the respective phase. When the proteins are energetically rather indifferent to the density of the amphiphiles, they will be localized at the line boundary between the (two-dimensional) liquid expanded and condensed phases. In between these two limiting cases, a delocalization transition of the proteins takes place. This transition is accessible by changing the temperature or the amount of incorporated protein. These findings are in agreement with recent fluorescence microscopy experiments. Our results also apply to lipid multicomponent membranes showing coexistence of distinct fluid phases.

Affiliated with

Also associated with

No associations

Rating

Protein Adsorption on Lipid Monolayers at their Coexistence Region does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Protein Adsorption on Lipid Monolayers at their Coexistence Region, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein Adsorption on Lipid Monolayers at their Coexistence Region will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-680958