Probing Noise in Gene Expression and Protein Production

Details Probing Noise in Gene Expression and Protein Production Probing Noise in Gene Expression and Protein Production

2009-02-05

arxiv.org/abs/0902.0941v1

Biology

Quantitative Biology

Biomolecules

10 pages, 3 figures, supplementary information on request

Scientific paper

We derive exact solutions of simplified models for the temporal evolution of the protein concentration within a cell population arbitrarily far from the stationary state. We show that monitoring the dynamics can assist in modeling and understanding the nature of the noise and its role in gene expression and protein production. We introduce a new measure, the cell turnover distribution, which can be used to probe the phase of transcription of DNA into messenger RNA.

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