Polymer Translocation in Crowded Environments

Details Polymer Translocation in Crowded Environments Polymer Translocation in Crowded Environments

2007-03-30

arxiv.org/abs/cond-mat/0703796v1

Physics

Condensed Matter

Soft Condensed Matter

4 figures

Scientific paper

10.1103/PhysRevLett.99.228106

We study the effect of the crowded nature of the cellular cytoplasm on the translocation of a polymer through a pore in a membrane. By systematically treating the entropic penalty due to crowding, we show that the translocation dynamics are significantly altered, leading to novel scaling behaviors of the translocation time in terms of chain length. We also observe new and qualitatively different translocation regimes depending upon the extent of crowding, transmembrane chemical potential asymmetry, and polymer length.

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