Partition-Induced Vector Chromatography in Microfluidic Devices

Details Partition-Induced Vector Chromatography in Microfluidic Devices Partition-Induced Vector Chromatography in Microfluidic Devices

2010-05-18

arxiv.org/abs/1005.3229v1

Physics

Condensed Matter

Statistical Mechanics

Scientific paper

The transport of Brownian particles in a slit geometry in the presence of an arbitrary two-dimensional periodic energy landscape and driven by an external force or convected by a flow field is investigated by means of macrotransport theory. Analytical expressions for the probability distribution and the average migration angle of the particles are obtained under the Fick-Jackobs approximation. The migration angle is shown to differ from the orientation angle of the driving field and to strongly depend on the physical properties of the suspended species, thus providing the basis for vector chormatography, in which different species move in different directions and can be continuously fractionated. The potential of microfluidic devices as a platform for partition-induced vector chromatography is demonstrated by considering the particular case of a piece-wise constant, periodic potential that, in equilibrium, induces the spontaneous partition of different species into high and low concentration stripes, and which can be easily fabricated by patterning physically or chemically one of the surfaces of a channel. The feasibility to separate different particles of the same and different size is shown for systems in which partition is induced via 1g-gravity and Van der Waals interactions in physically and chemically patterned channels, respectively.

Affiliated with

Also associated with

No associations

Rating

Partition-Induced Vector Chromatography in Microfluidic Devices does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Partition-Induced Vector Chromatography in Microfluidic Devices, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Partition-Induced Vector Chromatography in Microfluidic Devices will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-58440