On the Hypercube Structure of the Genetic Code

Details On the Hypercube Structure of the Genetic Code On the Hypercube Structure of the Genetic Code

2002-04-02

arxiv.org/abs/cond-mat/0204044v1

In H.A.Lim and C.A.Cantor (eds.), Proc. Bioinformatics and Genome Research, p. 445 (World Scientific, 1994)

Physics

Condensed Matter

Soft Condensed Matter

14 pages, 7 figures

Scientific paper

A representation of the genetic code as a six-dimensional Boolean hypercube is proposed. It is assumed here that this structure is the result of the hierarchical order of the interaction energies of the bases in codon-anticodon recognition. The proposed structure demonstrates that in the genetic code there is a balance between conservatism and innovation. Comparing aligned positions in homologous protein sequences two different behaviors are found: a) There are sites in which the different amino acids present may be explained by one or two "attractor nodes" (coding for the dominating amino acid(s)) and their one-bit neighbors in the codon hypercube, and b) There are sites in which the amino acids present correspond to codons located in closed paths in the hypercube. The structure of the code facilitates evolution: the variation found at the variable positions of proteins do not corresponds to random jumps at the codon level, but to well defined regions of the hypercube.

Affiliated with

Also associated with

No associations

Rating

On the Hypercube Structure of the Genetic Code does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with On the Hypercube Structure of the Genetic Code, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and On the Hypercube Structure of the Genetic Code will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-316344