Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
2011-02-21
Physics
Condensed Matter
Soft Condensed Matter
6 pages, 7 figures
Scientific paper
In this paper we explore relevant electrical properties of two olfactory receptors (ORs), one from rat OR I7 and the other from human OR 17-40, which are of interest for the realization of smell nanobiosensors. The investigation compares existing experiments, coming from electrochemical impedance spectroscopy, with the theoretical expectations obtained from an impedance network protein analogue, recently developed. The changes in the response due to the sensing action of the proteins are correlated with the conformational change undergone by the single protein. The satisfactory agreement between theory and experiments points to a promising development of a new class of nanobiosensors based on the electrical properties of sensing proteins.
Alfinito Eleonora
Millithaler Jean-Francois
Reggiani Letizia
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