Multiple stalk formation as a pathway of defect-induced membrane fusion

Details Multiple stalk formation as a pathway of defect-induced membrane fusion Multiple stalk formation as a pathway of defect-induced membrane fusion

2004-03-29

arxiv.org/abs/cond-mat/0403702v1

Physics

Condensed Matter

Soft Condensed Matter

Scientific paper

10.1140/epje/i2004-10005-5

We propose that the first stage of membrane fusion need not be the formation of a single stalk. Instead, we consider a scenario for defect-induced membrane fusion that proceeds cooperatively via multiple stalk formation. The defects (stalks or pores) attract each other via membrane-mediated capillary interactions that result in a condensation transition of the defects. The resulting dense phase of stalks corresponds to the so-called fusion intermediate.

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