Modelling DNA at the mesoscale: a challenge for nonlinear science?

Details Modelling DNA at the mesoscale: a challenge for nonlinear science? Modelling DNA at the mesoscale: a challenge for nonlinear science?

2008-08-06

arxiv.org/abs/0808.0799v1

Nonlinearity 21, 6 (2008) T91-T100

Physics

Condensed Matter

Statistical Mechanics

Invited paper, in the series "Open Problems" of Nonlinearity

Scientific paper

10.1088/0951-7715/21/6/T02

When it is viewed at the scale of a base pair, DNA appears as a nonlinear lattice. Modelling its properties is a fascinating goal. The detailed experiments that can be performed on this system impose constraints on the models and can be used as a guide to improve them. There are nevertheless many open problems, particularly to describe DNA at the scale of a few tens of base pairs, which is relevant for many biological phenomena.

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