Investigation of a new conformation of double stranded DNA

Details Investigation of a new conformation of double stranded DNA Investigation of a new conformation of double stranded DNA

2007-04-27

arxiv.org/abs/0704.3753v2

Physics

Condensed Matter

Soft Condensed Matter

Scientific paper

It had been proposed that overstretching double stranded DNA from the 5-5 ends will produce a new fiber form of dsDNA that is narrower than the S form that has been suggested to result when the dsDNA is overstretched from the 3-3 ends. We present the first comparison of the structures that result when dsDNA is overstretched from the 5-5, 3-3, and 3-5 ends and show that the stability of the overstretched form depends on the ends to which the force is applied. The stability also depends strongly on the ionic environment as well as the presence of reagents that bind to ssDNA.

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