Impact of loop statistics on the thermodynamics of RNA folding

Details Impact of loop statistics on the thermodynamics of RNA folding Impact of loop statistics on the thermodynamics of RNA folding

2008-02-22

arxiv.org/abs/0802.3272v2

Phys. Rev. Lett. 101, 048103 (2008)

Physics

Condensed Matter

Soft Condensed Matter

4 pages, 3 figures, including supplementary information

Scientific paper

10.1103/PhysRevLett.101.048103

Loops are abundant in native RNA structures and proliferate close to the unfolding transition. By including a statistical weight ~ l^{-c} for loops of length l in the recursion relation for the partition function, we show that the calculated heat capacity depends sensitively on the presence and value of the exponent c, even of short t-RNA. For homo-RNA we analytically calculate the critical temperature and critical exponents which exhibit a non-universal dependence on c.

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