Physics – Condensed Matter – Mesoscale and Nanoscale Physics
Scientific paper
2010-04-30
J. Chem. Phys. 133, 124105 (2010)
Physics
Condensed Matter
Mesoscale and Nanoscale Physics
10 pages, 4 figures
Scientific paper
10.1063/1.3483676
Magnetic Resonance Imaging (MRI) can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due to lack of detection sensitivity. Here we analyze the use of a nitrogen-vacancy center in diamond as a magnetic sensor for nanoscale nuclear spin imaging and spectroscopy. We examine the ability of such a sensor to probe the fluctuations of the "classical" dipolar field due to a large number of neighboring nuclear spins in a densely protonated sample. We identify detection protocols that appropriately take into account the quantum character of the sensor and find a signal-to-noise ratio compatible with realistic experimental parameters. Through various example calculations we illustrate different kinds of image contrast. In particular, we show how to exploit the comparatively long nuclear spin correlation times to reconstruct a local, high-resolution sample spectrum.
Cappellaro Paola
Goldstein Garry
Hodges James S.
Jiang Luo-Luo
Lukin Mikhail D.
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