Force Dependence of the Michaelis Constant in a Two-State Ratchet Model for Molecular Motors

Details Force Dependence of the Michaelis Constant in a Two-State Ratchet Model for Molecular Motors Force Dependence of the Michaelis Constant in a Two-State Ratchet Model for Molecular Motors

2000-12-05

arxiv.org/abs/cond-mat/0012057v1

Physical Review Letters 86 (2001), 1134--1137

Physics

Condensed Matter

Statistical Mechanics

4 pages, 3 eps figures, accepted for publication on Physical Review Letters

Scientific paper

10.1103/PhysRevLett.86.1134

We present a quantitative analysis of recent data on the kinetics of ATP hydrolysis, which has presented a puzzle regarding the load dependence of the Michaelis constant. Within the framework of coarse grained two-state ratchet models, our analysis not only explains the puzzling data, but provides a modified Michaelis law, which could be useful as a guide for future experiments.

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