Entropically Driven Helix Formation

Physics – Condensed Matter – Soft Condensed Matter

Scientific paper

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5 pages, one included figure

Scientific paper

10.1126/science.1106243

The helix is a ubiquitous motif for biopolymers. We propose a heuristic, entropically based model that predicts helix formation in a system of hard spheres and semiflexible tubes. We find that the entropy of the spheres is maximized when short stretches of the tube form a helix with a geometry close to that found in natural helices. Our model could be directly tested with wormlike micelles as the tubes, and the effect could be used to self-assemble supramolecular helices.

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