Effect of defects on thermal denaturation of DNA Oligomers

Details Effect of defects on thermal denaturation of DNA Oligomers Effect of defects on thermal denaturation of DNA Oligomers

2001-05-03

arxiv.org/abs/cond-mat/0105054v2

Physics

Condensed Matter

Statistical Mechanics

11 pages including 5 postscript figure; To be appear in Phys. Rev. E

Scientific paper

10.1103/PhysRevE.64.042901

The effect of defects on the melting profile of short heterogeneous DNA chains are calculated using the Peyrard-Bishop Hamiltonian. The on-site potential on a defect site is represented by a potential which has only the short-range repulsion and the flat part without well of the Morse potential. The stacking energy between the two neigbouring pairs involving a defect site is also modified. The results are found to be in good agreement with the experiments.

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