Depletion effects and loop formation in self-avoiding polymers

Details Depletion effects and loop formation in self-avoiding polymers Depletion effects and loop formation in self-avoiding polymers

2006-10-09

arxiv.org/abs/cond-mat/0610219v1

Physics

Condensed Matter

Soft Condensed Matter

4 pages, 3 figures

Scientific paper

10.1103/PhysRevLett.97.178302

Langevin dynamics is employed to study the looping kinetics of self-avoiding polymers both in ideal and crowded solutions. A rich kinetics results from the competition of two crowding-induced effects: the depletion attraction and the enhanced viscous friction. For short chains, the enhanced friction slows down looping, while, for longer chains, the depletion attraction renders it more frequent and persistent. We discuss the possible relevance of the findings for chromatin looping in living cells.

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