Conformation changes and folding of proteins mediated by Davidov's soliton

Details Conformation changes and folding of proteins mediated by Davidov's soliton Conformation changes and folding of proteins mediated by Davidov's soliton

1999-11-02

arxiv.org/abs/cond-mat/9911004v1

Physics

Condensed Matter

14 pages, 2 figures

Scientific paper

We suggest that Davidov's solitons, propagating through the backbone of a protein, can mediate conformational transition and folding of a protein to its native state. A simple toy model is presented in which a Non Linear Schrodinger (NLS) field interacts with another field phi, corresponding to the conformation angles of the protein. The interaction provides the conformation field with the energy needed in order to overcome energy barriers for folding, thus avoiding the need for stochastic thermal activation. Such a transition is therefore a deterministic controled process.The soliton is compensated for its energy loss by absorption of the energy gained in the folding process. This scenario does not change significantly even in the presence of imposed disorder, provided that the initial momentum of the soliton is large enough.

Affiliated with

Also associated with

No associations

Rating

Conformation changes and folding of proteins mediated by Davidov's soliton does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Conformation changes and folding of proteins mediated by Davidov's soliton, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conformation changes and folding of proteins mediated by Davidov's soliton will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-714830