Complexation in Polyelectrolyte Solution with Divalent Surfactant

Details Complexation in Polyelectrolyte Solution with Divalent Surfactant Complexation in Polyelectrolyte Solution with Divalent Surfactant

2003-12-18

arxiv.org/abs/cond-mat/0312498v1

Physics

Condensed Matter

Soft Condensed Matter

10 pages and 6 figures

Scientific paper

We study a simple model of DNA divalent cationic surfactant complexation. We find that the combination of electrostatic and hydrophobic effects leads to a cooperative phenomenon in which as the amphiphile is added to the solution containing DNA, a large fraction of the DNA's charge is neutralized by the condensed divalent cationic surfactants, forming the surfoplex. This binding transition occurs for concentrations that are lower for divalent than for monovalent surfactants. Since the electrostatic strength is larger in the first case and the amount of surfactant lower, we suggest that multivalent amphiphilic molecules would be more efficient than monovalent for transfection.

Affiliated with

Also associated with

No associations

Rating

Complexation in Polyelectrolyte Solution with Divalent Surfactant does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Complexation in Polyelectrolyte Solution with Divalent Surfactant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Complexation in Polyelectrolyte Solution with Divalent Surfactant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-307940