Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
2006-09-12
Physics
Condensed Matter
Soft Condensed Matter
88 pages, 39 figures, accepted to Physics Reports, version with higher resolution figures available at http://www.mrl.ucsb.e
Scientific paper
10.1016/j.physrep.2006.08.003
We discuss the role coarse-grained models play in the investigation of the structure and thermodynamics of bilayer membranes, and we place them in the context of alternative approaches. Because they reduce the degrees of freedom and employ simple and soft effective potentials, coarse-grained models can provide rather direct insight into collective phenomena in membranes on large time and length scales. We present a summary of recent progress in this rapidly evolving field, and pay special attention to model development and computational techniques. Applications of coarse-grained models to changes of the membrane topology are illustrated with studies of membrane fusion utilizing simulations and self-consistent field theory.
Katsov Kirill
Mueller Marcus
Schick Michael
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