Apparent Persistence Length Renormalization of Bent DNA

Details Apparent Persistence Length Renormalization of Bent DNA Apparent Persistence Length Renormalization of Bent DNA

2005-01-17

arxiv.org/abs/cond-mat/0501379v1

Physics

Condensed Matter

Soft Condensed Matter

4 pages, 2 figures

Scientific paper

10.1103/PhysRevE.72.041905

We derive the single molecule equation of state (force-extension relation) for DNA molecules bearing sliding loops and deflection defects. Analytical results are obtained in the large force limit by employing an analogy with instantons in quantum mechanical tunneling problems. The results reveal a remarkable feature of sliding loops - an apparent strong reduction of the persistence length. We generalize these results to several other experimentally interesting situations ranging from rigid DNA-protein loops to the problem of anchoring deflections in AFM stretching of semiflexible polymers. Expressions relating the force-extension measurements to the underlying loop/boundary deflection geometry are provided and applied to the case of the GalR-loop complex. The theoretical predictions are complemented and quantitatively confirmed by MD simulations.

Affiliated with

Also associated with

No associations

Rating

Apparent Persistence Length Renormalization of Bent DNA does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Apparent Persistence Length Renormalization of Bent DNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparent Persistence Length Renormalization of Bent DNA will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-237862