An Effective Membrane Model of the Immunological Synapse

Details An Effective Membrane Model of the Immunological Synapse An Effective Membrane Model of the Immunological Synapse

2003-04-08

arxiv.org/abs/cond-mat/0304202v1

Physics

Condensed Matter

Soft Condensed Matter

6 pages, 3 figures, submitted for publication

Scientific paper

10.1103/PhysRevLett.91.208101

The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T Cells and antigen presenting cells (APCs) during recognition. The synapse is implicated in information transfer between cells, and is characterized by different spatial patterns of receptors at different stages in the life cycle of T cells. We obtain a minimalist model that captures this experimentally observed phenomenology. A functional RG analysis provides further insights.

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