Accurate determination of elastic parameters for multi-component membranes

Details Accurate determination of elastic parameters for multi-component membranes Accurate determination of elastic parameters for multi-component membranes

2006-12-21

arxiv.org/abs/cond-mat/0612554v3

Physics

Condensed Matter

Soft Condensed Matter

(*) authors contributed equally, 6 pages, 3 figures, 1 table; added insets to figure 3

Scientific paper

Heterogeneities in the cell membrane due to coexisting lipid phases have been conjectured to play a major functional role in cell signaling and membrane trafficking. Thereby the material properties of multiphase systems, such as the line tension and the bending moduli, are crucially involved in the kinetics and the asymptotic behavior of phase separation. In this Letter we present a combined analytical and experimental approach to determine the properties of phase-separated vesicle systems. First we develop an analytical model for the vesicle shape of weakly budded biphasic vesicles. Subsequently experimental data on vesicle shape and membrane fluctuations are taken and compared to the model. The combined approach allows for a reproducible and reliable determination of the physical parameters of complex vesicle systems. The parameters obtained set limits for the size and stability of nanodomains in the plasma membrane of living cells.

Affiliated with

Also associated with

No associations

Rating

Accurate determination of elastic parameters for multi-component membranes does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Accurate determination of elastic parameters for multi-component membranes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Accurate determination of elastic parameters for multi-component membranes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-21706