A microfluidic device based on droplet storage for screening solubility diagrams

Details A microfluidic device based on droplet storage for screening solubility diagrams A microfluidic device based on droplet storage for screening solubility diagrams

2007-04-04

arxiv.org/abs/0704.0569v1

Physics

Condensed Matter

Soft Condensed Matter

Scientific paper

This work describes a new microfluidic device developed for rapid screening of solubility diagrams. In several parallel channels, hundreds of nanoliter-volume droplets of a given solution are first stored with a gradual variation in the solute concentration. Then, the application of a temperature gradient along these channels enables us to read directly and quantitatively phase diagrams, concentration vs. temperature. We show, using a solution of adipic acid, that we can measure ten points of the solubility curve in less than 1 hr and with only 250 $\mu$L of solution.

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