A hierarchical scheme for cooperativity and folding in proteins

Details A hierarchical scheme for cooperativity and folding in proteins A hierarchical scheme for cooperativity and folding in proteins

1997-01-10

arxiv.org/abs/cond-mat/9701075v3

Physics

Condensed Matter

4 pages RevTeX, 4 Postscript figures. Contents substantially revised compared to previous version

Scientific paper

We propose a protein model based on a hierarchy of constraints that force the
protein to follow certain pathways when changing conformation. The model
exhibits a first order phase transition, cooperativity and is exactly solvable.
It also shows an unexpected symmetry between folding and unfolding pathways as
suggested by a recent experiment.

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