Pattern formation inside bacteria: fluctuations due to low copy number of proteins

Details Pattern formation inside bacteria: fluctuations due to low copy number of proteins Pattern formation inside bacteria: fluctuations due to low copy number of proteins

2003-02-20

arxiv.org/abs/cond-mat/0302409v1

Phys. Rev. Lett. 90 128102 (2003)

Physics

Condensed Matter

Statistical Mechanics

4 pages, 3 figures, accepted for publication in Phys. Rev. Lett

Scientific paper

10.1103/PhysRevLett.90.128102

We examine fluctuation effects due to the low copy number of proteins involved in pattern-forming dynamics within a bacterium. We focus on a stochastic model of the oscillating MinCDE protein system regulating accurate cell division in E. coli. We find that, for some parameter regions, the protein concentrations are low enough that fluctuations are essential for the generation of patterns. We also examine the role of fluctuations in constraining protein concentration levels.

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