Shear Unzipping of DNA

Details Shear Unzipping of DNA Shear Unzipping of DNA

2009-04-09

arxiv.org/abs/0904.1611v1

J. Phys. Chem. B. 113, (12) pp 3831-3836 (2009)

Physics

Condensed Matter

Soft Condensed Matter

8 pages, 2 column, 6 figures

Scientific paper

10.1021/jp808232p

We study theoretically the mechanical failure of a simple model of double stranded DNA under an applied shear. Starting from a more microscopic Hamiltonian that describes a sheared DNA, we arrive at a nonlinear generalization of a ladder model of shear unzipping proposed earlier by deGennes [deGennes P. G. C. R. Acad. Sci., Ser. IV; Phys., Astrophys. 2001, 1505]. Using this model and a combination of analytical and numerical methods, we study the DNA "unzipping" transition when the shearing force exceeds a critical threshold at zero temperature. We also explore the effects of sequence heterogeneity and finite temperature and discuss possible applications to determine the strength of colloidal nanoparticle assemblies functionalized by DNA.

Affiliated with

Also associated with

No associations

Rating

Shear Unzipping of DNA does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Shear Unzipping of DNA, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Shear Unzipping of DNA will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-673280