Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle

Details Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle

2000-02-08

arxiv.org/abs/cond-mat/0002117v1

Physics

Condensed Matter

Statistical Mechanics

4 pages, RevTex, 4 eps figures

Scientific paper

10.1103/PhysRevLett.84.3009

A fascinating and open question challenging biochemistry, physics and even geometry is the presence of highly regular motifs such as alpha-helices in the folded state of biopolymers and proteins. Stimulating explanations ranging from chemical propensity to simple geometrical reasoning have been invoked to rationalize the existence of such secondary structures. We formulate a dynamical variational principle for selection in conformation space based on the requirement that the backbone of the native state of biologically viable polymers be rapidly accessible from the denatured state. The variational principle is shown to result in the emergence of helical order in compact structures.

Affiliated with

Also associated with

No associations

Rating

Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle does not yet have a rating. At this time, there are no reviews or comments for this scientific paper.

If you have personal experience with Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFWR-SCP-O-558319