Physics – Condensed Matter – Soft Condensed Matter
Scientific paper
2009-12-12
Physics
Condensed Matter
Soft Condensed Matter
8 pages, 10 figures
Scientific paper
We develop a simple model to study the effects of an applied force on the melting of a double stranded DNA (dsDNA). Using this model, we could study the stretching, unzipping, rupture and slippage like transition in a dsDNA. We show that in absence of an applied force, the melting temperature and the melting profile of dsDNA strongly depend on the constrained imposed on the ends of dsDNA. The nature of the phase boundary which separates the zipped and the open state for the shearing like transition is remarkably different than the DNA unzipping
Giri Debaprasad
Kumar Sanjeev
Singh Amit Raj
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