Finite-size effects in intracellular microrheology

Physics – Condensed Matter – Soft Condensed Matter

Scientific paper

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6 pages 2 figures. To appear in the Journal of Chemical Physics

Scientific paper

10.1063/1.2241190

We propose a model to explain finite-size effects in intracellular microrheology observed in experiments. The constrained dynamics of the particles in the intracellular medium, treated as a viscoelastic medium, is described by means of a diffusion equation in which interactions of the particles with the cytoskeleton are modelled by a harmonic force. The model reproduces the observed power-law behavior of the mean-square displacement in which the exponent depends on the ratio between particle-to-cytoskeleton-network sizes.

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